User blog comment:Woohoot/Things that totally could happen, but won't cause... Manga.../@comment-2226235-20150522040923

I'm actually not sure if the other fighters could take Doflamingo, even the way he is now. Remember, the only one who stood a chance against Luffy (other than Burgess) was Chinjao so I don't think they could beat Doflamingo. As for Mansherry, we don't know where she is right now and we also don't know how Gear Fourth works, so her abilities might not even work on Luffy the way he is now.