Love Sickness

Love Sickness is a particular disease that seems to be contracted by the empresses of the Kuja tribe. This happens when they fall in love with a man. If they suppress their emotions, then it weakens them and eventually leads them to death. This disease killed many Kuja empresses in the past. It is unknown if the illness can be contracted by normal Kuja citizens.

In order to cure the disease, if the empresses accept their emotions and follow the loved one. This means that leaving Amazon Lily seems to be a prerequisite for the survival of the recipient, since only the former Empress Gloriosa is currently the only known survivor, and was known to have left the island at some point prior to returning. She also implied that if Hancock, another sufferer of the disease, follows her beloved Luffy (which means leaving the island), she wouldn't die.

Known People to be Afflicted

 * Many empresses of the past: Died because of their suppressed emotions.
 * Elder Nyon: She somehow survived the illness after falling in love with a man, even though their relationship was unknown.
 * Boa Hancock: Having fallen in love with Monkey D. Luffy, she contracted the disease. However, when she accepted her feelings and decided to go with Luffy; is unknown as to whether or not she is cured.