User blog comment:AYET/The many defeats of Monkey D Luffy/@comment-6920514-20130703015627

You certainly picked the 3 best ones AYET so I'm gonna go in a different direction. Akainu killed Ace right in front of him and later punched him through Jinbe. They didn't really fight much one on one but Akainu was the only one that broke Luffy's spirit. That was a complete and total defeat. The only one he needed help to bounce back from. Another great blog, AYET.