Vegapunk

Dr. Vegapunk (Dr.ベガパンク) is the leading scientist in the employment of the Marines. His work includes discovering the secrets and uses of Seastone, the secrets of how Devil Fruit powers work, and various other scientific achievements. He has a bodyguard named Sentomaru and hails from the technologically advanced island of Karakuri. Many of the inventions and blueprints in his house were destroyed by Franky during the Nightmare of Barujimoa. The explosion, however, uncovered another one of his labs, in which Franky spent two years studying and improving himself. Despite Vegapunk's achievements, he has yet to make a personal appearance in the series.

Personality
In his youth, he was a kindhearted person who cared very much for the inhabitants of his island, willing to help them with his inventions. He is considered the island's pride and joy, and the residents are still hoping for his return. He also respects the wishes of his colleagues, as he agreed to give a command that Kuma himself requested.

Bartholomew Kuma
Vegapunk seems to have a good enough relationship to grant him his final wish as a human being. Vegapunk programmed Kuma to protect the Straw Hat Pirates' ship until they returned. It is very likely that Vegapunk highly respects Kuma's strength, as he modified Kuma to be the prototype Pacifista, and he let Kuma do things that go against the World Government, as well as granting him his last wish by including a mission into his programming that Kuma himself had requested.

Abilities and Powers
Vegapunk is a knowledgeable scientist whose scientific expertise is said to be at least 500 years ahead of his contemporaries. It seems that even in his youth the scientist was a genius, but lacked the skills and funds to develop his inventions. Regardless, his creations and blueprints that he left behind were considered priceless, and that any damage inflicted to them is considered a crime.

Through his research he discovered ways of allowing Marine ships to pass through the Calm Belts without fear of Sea King attacks by covering the bottom of the ships with Kairoseki. He also discovered exactly how Devil Fruit powers are transferred over to a user, and was the scientist behind the method of adding Devil Fruit powers to inanimate objects, such as swords or guns.

He is the one who modified Bartholomew Kuma into a cyborg, and has produced many Pacifista replicas of him, granting them some of the abilities of Kizaru's Devil Fruit in the process. These replicas bleed actual blood, and lack Kuma's own Devil Fruit powers. After the two year time skip, Sentomaru revealed that the latest Pacifista had been modified further, but these have yet to be seen.

Scientific Achievements

 * Kairoseki usage
 * Restraining items (nets, handcuffs, stun batons, etc)
 * Covering the bottom of ships for avoiding Sea Kings
 * Devil Fruit research
 * What Devil Fruits really are.
 * How Devil Fruits react with humans.
 * What would happen if a person eats more than one Devil Fruit.
 * Allowing objects to "eat" the fruit.
 * Research into the Pika Pika no Mi.
 * Pacifista project
 * Modifying Bartholomew Kuma into a cyborg.
 * Creating cybernetic replicates of Kuma.
 * Installing devices that have a similar ability as the Pika Pika no Mi to project explosive lasers.
 * Other
 * Climate Control (unfinished, destroyed)
 * Many blueprints of unmade creations (destroyed)
 * The cyborg animals
 * Various weapons
 * Studying everything from battleships to human cells

Trivia

 * In relation to a question asked by a fan stating "How come Luffy's Devil Fruit was already in the Devil Fruit encyclopedia when he ate it?" Oda hinted that Vegapunk might know what Devil Fruits really are.
 * Vegapunk is comparable to Leonardo da Vinci, who is often thought of in modern history as a man who was ahead of his time. Some historians also go so far to say Leonardo was more than 5 centuries ahead of his time, just as Vegapunk is likewise considered 500 years ahead of his time.

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Vegapunk