User blog comment:Bluefox87/Regarding the aftereffects of gear 4th ch 785/@comment-24769684-20150513110645/@comment-24769684-20150513173228

Well, judging from what it says on the Ope Ope no Mi page, the process logically halts your age for all time, allowing you to live forever. However, it doesn't make you invulnerable from getting wounded and stuff like that. I'm not sure. Doflamingo's main intent with this fruit is to steal the treasure of Mariejois, so I'm betting whatever the treasure is, it will take a loong time to use properly, meaning only an immortal could "assemble" it or whatnot. (I'm still betting the treasure is a Poneglyph)