Episode 601

"Shaking Up the New World - Caesar's Nightmarish Experiment" is the 601st episode of the One Piece anime.

Short Summary
At the lab, the G-5 Marine soldiers are banging on the door, demanding entry. Meanwhile, the children were returned to the Lab where Caesar ordered his subordinates to make sure they don't escape again. However, Mocha begins to regain her senses, seeing Caesar's subordinates as monsters.

Within Ceasar's private quarters, Vergo and Monet are waiting for Caesar's return. As soon as he arrived, he revealed that he made a deal with Law in the past to give his heart to him and in exchange he will get to keep Monet's. He shows Law that Vergo is now in possession of his heart, keeping him on a leash. Caesar currently has Smoker's heart with him, but before he would torture him, Monet informs Caesar that the broadcast is ready.

In the broadcast, it is shown that a very large candy is being offered to Smiley, which is a deadly weapon known as Shinokuni. Caesar ordered the subordinates that brought the candy to remove their suits and quickly return to the Lab, which they complied. As Zoro's Group are being chased by Smiley, The poison beast saw the candy and promtly swollowed it, ignoring the false heartfelt words from Caesar. Caesar then laughs as Smiley starts spasing uncontrollably while everyone watching wonders what happening to the creature.

Anime Notes

 * The anime adds the following:
 * In addition to having a hallucination with seeing a person with a snake head, Mocha also sees a person with a frog head and a person with a lizard head.
 * Monet serving coffee to Vergo and asking if he would accept it with milk.
 * When Caesar was feigning worry for his subordinates, he is seen holding a bottle of the acid that was used to damage the sled used by his subordinates.
 * The preview at the end is shortened for the first time since Episode 580.