User blog comment:Kaido King of the Beasts/Kaido Arc Discussion/@comment-10543621-20140427232831

I personally vote for an all out war breaking out with both Big mom and Kaido wanting Luffy's head, thereby clashing with each other as well, giving rise to a three way fight. The marines of course gets themselves involved and everything just becomes a huge mess.

But before it reaches that stage, I'm predicting at least 2 or 3 more arcs. Too quick for a giant war really. If anything, I think neither Kaido and Big Mom has enough reasons to start a war just to go after Luffy yet. We've seen that the Yonkou are generally rational and well planned individuals. Otherwise they wouldn't be able to rule for so long. I believe they still see Luffy as a fledgling and would probably watch him with curiousity. The strawhats need to stir a few more shit before they see him as a real threat.

I'm thinking a few more arcs where they defeat some of their major leaders or something. Maybe we'll have an arc where the strawhats destroy Kaido's Zoan army, which is not that far-fetched if we go along the lines of destroying artificial zoans, which could include the existing users... Now THAT should be enough to get him riled up, and the fight against them would be more than enough of a major arc, possibly involving multi alliances.