Lineage Factor

The Lineage Factor is the blueprint of life itself, present in all living organisms. It was discovered by a research team led by Dr. Vegapunk and Vinsmoke Judge.

Overview
All lifeforms have the Lineage Factor, and by manipulating it from a young age the growth of a lifeform can be changed. Eating a Devil Fruit affects one's lineage factor that allows them to gain a supernatural power.

SAD
By applying Lineage Factor, Caesar Clown was able to create SAD, a key ingredient used in the development of artificial Devil Fuits known as SMILES, as explained by Trafalgar Law.

Modified Humans
By manipulating the Lineage Factor of his pregnant wife, Sora and the four fetuses, Vinsmoke Judge could make his four sons Modified humans. While arguing with his wife he claim that he'll use this procedure solely on his kids. However, due to his wife's interference, only three of their children were born modified. After their birth, they ware further experimented on and drugged, in order to increase their development, along with their elder sister.

The subjects develop an Exoskeleton (外骨格), lose their emotions of compassion, have an increased healing ability, and with training, rapidly increase in strength and resilience to the point equaling an adult man while in their early childhood. Reiju was also modified so that she lost some of her emotions, and is unable to refuse her father's orders.

Cloning
Vinsmoke Judge conducted several researches and experiments with the Lineage Factor, becoming able to artificially manufacture human beings to fill the soldier ranks of Germa 66. Those soldiers are known as Clone Soldiers (複製 (クローン) 兵) and they are made without the knowledge of their origin.

Trivia

 * The Lineage Factor is a reference to DNA, the molecule that contains all the genetic information of the host organism.

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