Tree Fever

Tree Fever (樹熱) was a lethal disease that affected some Grand Line islands, 400 years ago.

Symptom and cure
The only one known symptom is the apparition of some black spots (resembling green rash or moss in the anime) on the skin. It can be transmitted from animals to plants and vice versa.

The only known cure so far is the Conine, a substance extracted form the Kona Tree.

Story
Four hundred years ago, this disease affected Jaya and the most of Shandian Tribe that believes it to be a curse of gods. To stop it, the dying priest Pantri order to sacrifice Mousse to the snake god Kashigami.

In the same moment, the botanic Montblanc Noland land on the island and find an affected indigenous named as Seto and curing him. After this he go to kill Kashigami to stop the sacrifice. After some initial misunderstandings, the botanic's been capable to use the Conine to cure all the tribe.

To stop the expanding of the disease, Noland and his crew break down the infected forest, also known as the sacre forest of Shandians.

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