Isshi-100

The Isshi 20 (イッシー・トゥエンティ, Isshī Tuenti, 20 Doctors in the English versions) are the twenty most skilled doctors of Drum Island ("isha" means "doctor"), whom Wapol took for himself in order to make his subjects grovel at his feet for their services. While they were under Wapol's control, they secretly despised and hated him as the rest of the people did, but gave in to the King in order to continue their research and refine their technique, which they hoped to one day use to help their compatriots. After Wapol was defeated, they were forgiven by the people of the island and rejoined them as part of the new Sakura Kingdom.

First Appearance: Chapter 136; Episode 82