User blog comment:The ASL Pirates/Will Someone other than Luffy Fight the Strongest Opponent?/@comment-5690257-20150627142525

Well as far as we know other straw hats that have fought against major antagonists for a minimum amount of time are (canon only so no stuff like Saga)

Zoro dealt the final blow to Morgan

Nami helped Luffy with Buggy

Vivi attacked Crocodile to no avail

Nami fought with Enel and helped Luffy deal the final blow

Lucci completely destroying Franky

The straw hats against Oars and trying to take down Moriah

Sanji trying to fight Doffy

But yeah it would be interesting although I think Law is already kinda filling that role