User blog comment:JustSomeDude.../761- Let's talk about Chapter 595!/@comment-24442815-20140919200836/@comment-71.13.82.190-20140919202601

His connections won't mean anything if he actually has to fight someone as strong as Kaido is said to be. As was already seen with Luffy making one "normal" punch to Doflamingo he can take it but it did still cause him a bit of pain. If Kaido is considered to be "strongest creature" then I would expect Doflamingo could just laugh of any punch.