User blog comment:Kaido King of the Beasts/Chapter 867: Suns and Daughters/@comment-9022101-20170601195801/@comment-97.81.27.42-20170602064151

I concur that Big Mom must have accidently ate Caramel, but I have two others: one that Caramel's power must have taken a toll that possibly lead to her disappearance; and there is the possibility that the CP agencies were behind it.