Mescal Cactus

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Mescal Cactus (メスカルサボテン) is a very small round cactus that causes hallucination. It grows in Sandora Desert. It first appeared in Chapter 162 and Episode 98 when Luffy ate one instead of Lizard Meat, without thinking twice about it. After eating it, Luffy felt like he was drowning and nearly attacked his crew. Tony Tony Chopper knew about the cactus and with his quick thinking, tranquilized Luffy, which caused the effect to wear off when Luffy awoke.

Trivia

 * Some species of cactus have a psychoactive chemical held within called Mescaline, the substance causes confusion of the senses (although not true hallucinations).This is most probably the origin of the name Mescal Cactus.