I honestly think Magu Magu is more threatning. Don't get me wrong, the Doku Doku is hella dangerous and almost ended Luffy and Blackbeard early, but the thing about the Doku Doku is that you actually have a cure for the poison while the Magu Magu is a much different story. Maybe when Magellan is in that red poison form, the cure is nine times outta ten useless, but the Magu Magu just seems more dangerous in a way since you don't have a cure for it.