After escaping from Totto Land, the Fire Tank Pirates head out toward their next quest: reuniting Chiffon with her twin sister, Lola. First, they steal an enemy ship and head toward Thriller Bark. However, they cannot cross the Red Line because Marines are guarding for the Levely, so they dock at Dressrosa to pick up supplies.
Upon landing at Dressrosa's West Port, they defeat two Marine soldiers and encounter a guitarist who mistakes Chiffon for Lola and greets her for finding a husband. After learning they are actually sisters, the guitarist informs them that Lola was in Dressrosa just some days before.
The crew decides to enter the city, which still exhibits the remains of the destruction caused during the events of the Dressrosa Arc, including the ground scarred by Doflamingo'sTorikago. Disguised, they start to look and ask for Lola among the citizens, until Vito finds several men collapsed to the ground due to a vacuum-kissing spree by Kyuin.
Meanwhile, the Germs Pirates attack Dressrosa, spreading their "Kiss-Kiss Germ" among the citizens, while its king is away, until the Fire Tank Pirates defeated the said crew. Chiffon got captured by the Marines and Gotti chases after her but is beaten up by her captors. Later, Bege and Vito were under attacked by the citizens who were infected by the "Kiss-Kiss Germ". Gotti got back up and went after Chiffon once again.