Chapter 454 is titled "Humming".
Color Spread: "Deadly Combat."
Luffy and Franky are fifty-three rounds deep into a boxing match, with no end in sight; all around the ring, a crowd of animal spectators (including Chopper) cheer on with cornermen Sanji and Usopp. High above, Robin dutifully keeps score.
The chapter starts off with Lola chasing Nami. Nami then exclaims that she is in fact a man, which calms the zombie down. After making friends with it, Absalom appears but Lola starts chasing him so Nami can escape. Back at the Thousand Sunny, Perona is raiding the ship when Hildon appears to summon her to Moria. At the bridge, Franky and Robin battle Tararan, but are ultimately trapped in his web. Brook then makes an entrance and defeats Tararan in one slash.
Lola keeps chasing Nami, with Usopp and Chopper trying to stop her. They fail, and Lola is ready to attack Nami. When she tries to kill her, Nami shouts that she is in fact a man. Lola believes her, and Nami asks her to be friends. When Absalom appears again, Lola runs towards him and Nami and the others find a chance to leave.
In Thousand Sunny, Perona is stealing the Straw Hats' treasures. Hildon appears and tells Perona that Moria is calling for a meeting. She goes to her room, just to find Absalom and Kumashi there already. Nami, Usopp and Chopper are hiding inside Kumashi just to participate in this meeting.
Outside, Franky and Robin witness Brook falling from the sky and lands badly on the ground. Tararan uses his web to reach them, but Robin and Franky trap him inside his webs while Franky deals some damage to him too. They think they defeated him, but he recovers and his spiders trap Robin and Franky.
Out of nowhere Brook appears in front of them, finishing off Tararan with a deadly slash.
- The scene in the cover appears in the 12th One Piece Opening Kaze o Sagashite".
- Nami befriends Lola.
- The Mysterious Four are called to a meeting with Moria, with Nami, Usopp and Chopper hijacking Kumashi to attend alongside Perona.
- Brook reveals his abilities as a swordsman, defeating Tararan.