In both the manga and anime, this saga does not have a main antagonist, following the "villain of the week" format, with each arc having independent antagonists. The first season of the live-action series adapted Monkey D. Garp as a main antagonist, to serve as the main threat.
With six arcs, this saga has the most canon arcs.
Most of the arcs of this saga were adapted in the first season of the live action series, with the exception of the Loguetown Arc.