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The Isshi-20 were the twenty most skilled doctors on Drum Island, whom Wapol took for himself in order to make his subjects dependent on him for their services.

The Isshi-100 are the Isshi-20 renamed two years after their introduction, as they have recruited eighty additional doctors, becoming a group of one hundred doctors.


They are one hundred different doctors who dress in scrubs with sunglasses. They constantly have surgery mask and gloves on them. They are all of varying height with similar builds and most of the time stand as if prepared for surgery. The Isshi-20 from two years ago are wearing pink scrubs, but the color of the scrubs the Isshi-100 are currently wearing remains unconfirmed.

Abilities and PowersEdit

The Isshi-20 were the some of the most highly skilled doctors of Drum Island, they were skilled enough to save Wapol's life even after he was decapitated.[1] As the Isshi-100, their capabilities as doctors remain to be seen.



Isshi 20

The Isshi-20, under Wapol's command.

During King Wapol's Doctor Hunt, he ordered all doctors on Drum Island to live under his direct command, while eliminating those who did not comply either by banishment or killing. This was done to force the citizens to grovel to Wapol for medical help, so his tyrannical rule would be unopposed.

The twenty doctors who complied became known as the Isshi-20, and while they remained under Wapol's control, they secretly despised and hated him as the rest of the people did. However, they gave in to the king in order to continue their research and refine their techniques. Upon seeing the rogue doctor Dr. Hiriluk's noble sacrifice, the Isshi-20 became determined not to give up and lose to him as doctors. To this end, they hoped to use their research and techniques to help their compatriots. When Wapol fled the kingdom due to a a fearsome enemy's attack, he took the Isshi-20 with him.[3]

Drum Island ArcEdit

After Wapol and his crew returned to Drum Island, Dalton struck Wapol down and the Isshi-20 used their medical skills to treat the latter.

After Wapol was defeated, they were forgiven by the people of the island and rejoined them as citizens of the new Sakura Kingdom.

From the Decks of the WorldEdit

Two years later, the Isshi-20 has grown to become the Isshi-100, working under Kureha at Sakura Kingdom's medical center.

They now have a new logo; a black flag combining the cross from Chopper's hat with a silhouette of what looks like Hiriluk's hat.[2]

Translation and Dub IssuesEdit

"Isshi" is derived from ishi (医師?), which means "doctor". In the English version, the Isshi-20 are accurately translated as "doctors" or "MDs", the last, meaning Doctor of Medicine (from the Latin Medicinae Doctor).


  1. 1.0 1.1 One Piece Manga and Anime — Vol. 15 Chapter 136 and Episode 82, The Isshi-20 make their debut.
  2. 2.0 2.1 One Piece Manga — Vol. 65 Chapter 637, cover story: From the Decks of the World Vol. 21, Kureha and the Isshi-100 are reintroduced.
  3. One Piece Manga and Anime — Vol. 15 Chapters 133134 and Episode 80, Dalton explains how Wapol and his men abandoned Drum when the Blackbeard Pirates attacked.

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Bliking Pirates
Members: Wapol  •  Chess   •  Kuromarimo   •  Chessmarimo  •  Isshi-20  •  Robson  •  Musshuru 
Ship(s): Bliking
Devil Fruit Based: Baku Baku no Mi  •  Noko Noko no Mi 
Weapon Based: Royal Drum Crown 7-Shot Bliking Cannon
Related Articles
Story Arc: Drum Island Arc  •  Wapol's Omnivorous Hurrah
Movies: Episode of Chopper Plus: Bloom in Winter, Miracle Sakura
Locations: Drum Island
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Drum Island
Royalty: Former King   •  Wapol   •  Dalton  •  Musshuru  
Others: Kureha  •  Hiluluk   •  Tony Tony Chopper   •  Negikuma Maria  •  Stool  •  Tamachibi  •  Isshi-100  •  Chess   •  Kuromarimo   •  Robson *
Devil Fruit Based: Baku Baku no Mi   •  Ushi Ushi no Mi, Model: Bison  •  Hito Hito no Mi   •  Noko Noko no Mi  
Related Articles
Locations: Drum Castle  •  Bighorn  •  Cocoa Weed  •  Gyasta  •  Robelle  •  Drum Rockies
Misc: Sakura Kingdom  •  Drum Ropeway
Story Arcs: Drum Island Arc  •  Post-Enies Lobby Arc  •  Chapter 0  •  Post-War Arc  •  Whole Cake Island Arc  •  Levely Arc
Cover Stories: Wapol's Omnivorous Hurrah  •  From the Decks of the World  •  From the Decks of the World: The 500,000,000 Man Arc
Movies: Episode of Chopper Plus: Bloom in Winter, Miracle Sakura
Others: Bliking Pirates  •  The Doctor Hunt  •  Levely
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Canon: Nako  •  Crocus  •  Kureha  •  Hiluluk   •  Tony Tony Chopper  •  Isshi-100  •  Ho  •  Potsun  •  Muret  •  Doc Q  •  Kurotsuru  •  Kyukyu  •  Marco  •  Hogback  •  Trafalgar D. Water Law  •  Marie  •  Belladonna  •  Fishbonen  •  Aladine  •  Tegata Ringana  •  Miyagi  •  Tristan  •  Époni  •  Masked Deuce  •  Gerth
Non-Canon: Zabal  •  Kobato  •  Nightin  •  Whitejack  •  Kiruko