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Eiichiro Oda will serve as executive producer for the series alongside Tomorrow Studios' CEO Marty Adelstein and President Becky Clements. Steven Maeda is the series' showrunner and, along with Matt Owens, an executive producer and writer.
With the series' announcement, Oda commented that "the first condition [he] presented is that the live-action [sic] will be faithful to the fans who have supported ‘One Piece’ for 20 years". A few days later, Adelstein predicted that its budget "could set a new record for the highest production cost in television drama history" as "the work's worldwide fame merits this scale of production". The series will reportedly begin with the East Blue Saga. In May 2020, Tomorrow Studios had planned to begin filming the series in South Africa by the end the year. However, in December Variety reported that One Piece had not "set a start date" in an article about South Africa's lifting of COVID-19 travel restrictions.
In September 2020, Matt Owens discussed adapting the series on a YouTube live-stream hosted by fans of the franchise. Owens explained that he hoped to introduce the franchise to new audiences through live-action version and that writers' ambition for each episode is to replicate the manga's ability to make readers "laugh," "cry" and "go 'holy shit!'"; however, the East Blue arc will be less episodic and the series' humor will be suited to contemporary Western sensibilities. Owens also recounted that he was given Oda's approval after explaining how significant the franchise had been in his life.
- On March 8, 2019, a listing for One Piece appeared on Netflix in the “American Programmes” category, but was removed the next day. It reappeared with the Netflix Original branding once the first season was announced in January 2020.