Players are able to interact with the Straw Hat Pirates by visiting rooms of the Thousand Sunny and having conversations with the crew. For example, players can train with Zoro or help the crew fight the enemies. In conversation, characters' reactions will also change based on the options you select. The game also includes summer and winter experiences formerly exclusive to Tokyo One Piece Tower.
Players can interact with Sanji in the kitchen, with Zoro on the ship's deck to train, and with Chopper in his medical offices to watch his examinations. They can also collect items from the crew by spotting them in the environment and hovering over them.
During combat, players operate cannons to shoot at enemy pirate ships and large enemies like the Kraken. Shooting enemies gives players points. Players also use the cannon to choose which Straw Hat Pirates will complete actions like attacking enemies or deflecting projectiles.
In the Tokyo One Piece Tower demo, eight players can play simultaneously. It is unknown if these features will be available in the console version. The game features two main adventures: Sea Battle Against the Marines and Repel the Kraken. Each adventure has multiple scenes.
Players board the Thousand Sunny as new deckhands and meet different members of the crew. An unidentified person speaking through Den Den Mushi acts as the main guide and narrator for the duration of the game.
Sea Battle Against the Marines
Players choose whether they want to visit Nami's Quarters to talk with Nami and Robin or the ship's Galley to talk with Sanji and Chopper. After they finish their conversation, the players return to the deck of the Sunny to Fight the Marines in a cannon battle, shooting to deflect cannonballs and barrels sent toward them by a fleet of Marine ships. They are divided into two teams, one red and one blue, competing for higher scores. Sanji and Zoro get into a dispute, and players use the cannons to choose which of them will defend against a giant cannonball.
Repel the Kraken
Players choose whether they want to visit Nami's Quarters to talk with Nami and Brook, the ship's Galley to talk with Sanji and Usopp, the Sick Bay to be examined by Chopper, or the Upper Deck to talk with Zoro and Franky. After the conversation scene, the players and the Straw Hat Pirates return to the deck of the Sunny to Fight the Kraken. Divided into teams again, players shoot at the Kraken and its tentacles. After the players damage and anger the creature, Robin uses Gigantesco Mano: Stomp to knock it out and send it back into the sea. Suddenly, Donquixote Doflamingo appears. Luffy fights him, and players choose what happens during an interactive cutscene. With the players' help, Luffy defeats Doflamingo.
The only playable character is an unnamed first-person protagonist. Players can interact with all of the Straw Hat Pirates.